According to Michael Dattoli, the use of advanced imaging and hypofractionation is essential to the delivery of radiation therapy. Intensity-modulated radiotherapy, image-guided therapy, proton beam therapy, and stereotactic body radiotherapy are examples of these advanced techniques. These techniques help deliver a higher dose to the target while sparing healthy tissue. However, they can be complicated due to uncertainties in imaging, treatment planning, and tumor size.
The use of hypofractionated radiotherapy reduces the number of radiation treatments needed. Because the patient receives less radiation, this form of treatment may improve the quality of life for patients. In addition, patients may require fewer sessions, which means fewer visits to the cancer center and fewer unpleasant side effects. In addition, the use of advanced imaging and hypofractionation reduces the amount of radiation exposure to healthy tissues, which can make treatment easier. Michael Dattoli thinks that the BELLA team is working to develop a new targeting technology that will focus lasers to higher intensities and generate higher-energy protons. The current focusing system only generates beams powerful enough to deliver FLASH radiotherapy to thin sheets. Higher-energy ion beams will penetrate deeper into living tissue. Jian-Hua Mao, co-author of the paper, said that the new technology may eventually be used in radiotherapy. Despite the limitations of conventional radiotherapy, advances in technology have improved its efficiency. Hypofractionated radiotherapy allows physicians to deliver larger doses over a shorter period of time. In addition to hypofractionation, the use of stereotactic body radiotherapy allows doctors to perform one to five treatments. This technique has also paved the way for safer, more efficient treatments. This method is now gaining wider acceptance due to the many benefits it offers. Recent studies have shown that the use of advanced radiation techniques has increased over time for patients with head and neck cancer. The National Cancer Database data shows that more patients are receiving advanced radiation therapy for this disease. Since 2004, advanced radiation therapy was used in 78% of relevant cases. However, disparities exist across racial, socioeconomic, and geographic groups. The researchers found that patients from minority and low-income backgrounds are less likely to receive advanced radiation techniques. Michael Dattoli feels that the use of imaging biomarkers allows clinicians to target areas at higher risk of radio-resistance and allow for biologically focused dose escalation. With the use of imaging during radiation therapy, including artificial intelligence, advanced imaging is essential to improve radiotherapy and reduce long-term toxicities. The future of radiation therapy will be based on the use of this technology. It is important to note that advanced imaging is only one of many tools in the field.
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